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3rd Berkeley-Stanford Summer Schools on
Synchrotron Radiation and its Applications in
Physical Sciences and Life Sciences
July 7-13, 2002
Final Program - Overview:
Sunday, July 7: Registration and Check-in at Elliot Program Center followed by welcome reception. Dinner in groups at local restaurants in Palo Alto
Monday, July 8: Joint morning session on Synchrotron Radiation and its application
Friday, July 12: Visit to SSRL and joint session with keynote lectures on cutting edge applications of synchrotron radiation.
Friday, July 12: Closing discussion and evening reception/BBQ
Saturday, July 13: Departure
Life Sciences Program 2002:
The Life Sciences Program 2002 will focus on structure determination methods in macromolecular crystallography from crystal screening to structure interpretation. A group of outstanding lecturers will teach approximately 40 students in an intensive training program throughout the week. Particular attention will be given to hands-on problems in current structural biology research. Students should prepare a one-page transparency describing their scientific problem for presentation to all of the participants during a dedicated session.
The program for Life Sciences Course includes a combined program with the Physical Sciences Course for Monday morning and all day Friday. The remaining formal Physical and Life Sciences sessions will be held in parallel. All students and lecturers will meet for joint breakfast, lunch and dinner sessions. The Life Sciences program, including the joint sessions, is outlined below.
Sunday
3:00 - 6:00: Registration and check-in at Elliot Program Center
5:30 - 7:00: Welcome of students and lecturers and reception
7:00 - 9:00: Dinner in groups at local restaurants
   
Monday
Joint Session-
7:30 - 8:30: Breakfast
8:45 - 10:15: Dave Attwood: Introduction to synchrotron radiation
10:15 - 10:45: Break
10:45 - 11:30 : Anders Nilsson: Interaction of synchrotron radiation with matter - the physical principles behind the experiment
11:30 - 12:15: Peter Kuhn: Synchrotrons, insertion devices and beamlines
12:00 - 1:30: Lunch
Parallel Session: (chaired by John Kuriyan, Tom Alber, and Peter Kuhn)
1:30 - 3:30: Crystallography - understanding the baseline
3:30 - 4:00: Break
4:00 - 5:30: Elspeth Garman: Diffraction theory and space groups
Evening Session:
5:30 - 7:30: Rejoin with Physical Sciences for an outdoors BBQ dinner
7:30 - 9:30: Evening session on student problems
   
Tuesday:  
7:30 - 8:30: Breakfast
8:30 - 9:30: Andrew Leslie: Principles of data reduction
9:30 - 10:30: Axel Brunger: Principles of phasing; phase determination
10:30 - 11:00: Break
11:00 - 12:00: Elspeth Garman: Data collection strategy and diffraction experiment
12:00 - 1:00: Lunch
1:00 - 2:00: Axel Brunger: Refinement and the fitting of data; model validation and model bias
2:00 - 3:00: Ana Gonzalez: Diffraction assessment, scattering analysis, strategy design
3:00 - 3:30: Break
3:30 - 4:30: Thomas Schneider: Heavy atom substructures
4:30 - 5:15: Paul Ellis: Alternative derivatives, alternative analysis
5:15 - 6:15: Rejoin with Physical Sciences for dinner at Ricker's
7:00 - 9:00: Software development workshop: Integrating crystallographic software with the experiment.
   
Wednesday  
7:30 - 8:30: Breakfast
8:30 - 9:30: Ashley Deacon: High throughput structural biology
9:30 - 10:30: Andrew Leslie: Practical aspects of data reduction and scaling
10:30 - 11:00: Break
11:00 - 12:00: Thomas Schneider: Solving heavy atom substructures - practical aspects
12:00 - 1:00: Lunch
1:00 - 2:00: Andrew Leslie: Non-crystallographic symmetry, density modification, and phase combination
2:00 - 3:00: Leslie Tari: Problem of model building and fitting
3:00 - 4:00: Ashley Deacon: Practical aspects of automated model building
4:00 - 4:15: Break
4:15 - 5:15: Paul Adams: Automation of refinement
5:15 - 6:15 Rejoin with Physical Sciences for dinner at Ricker's
7:00 - 9:00: Software development workshop: Integrating crystallographic software with the experiment
   
Thursday
7:30 - 8:30: Breakfast
8:30 - 9:45: Duncan McRee: XtalView et al
9:30 - 10:00 Charles Kissinger: Introduction to molecular replacement
10:00 - 10:30: Break
10:30 - 12:00: Charles Kissinger: Molecular replacement: evolutionary algorithms and fractional models
12:00 - 1:00: Lunch
1:00 - 2:00: Andrej Sali: Modeling of the structures of protein assemblies
2:00 - 3:00: Andrej Sali: Methods and applications of homology modeling
3:00 - 3:30: Break
3:30 - 5:15: Andrej Sali and Irimpan Mathews: Tutorial session on homology modeling
5:15 - 6:15: Rejoin with Physical Sciences for dinner at Ricker's
7:00 - 9:00: Evening session: Discussion of the impact of bioinformatics and computational tools on macromolecular crystallography
   
Friday:  
7:30 - 8:30: Breakfast
8:30 - 9:30 Helmut Wiedemann: Electron Accelerators as Synchrotron Radiation Sources
10:00 - 12:00: Tour of SSRL
12:00 - 1:00: Lunch at SSRL with SSRL staff (picnic area between LOS & SCS Buildings)
1:30 - 2:30: Doug Rees: Crystallography at the cutting edge
2:30 - 3:30: Jim Wells: Drug development - structural biology integrated in the drug discovery pipeline
3:30 - 4:00: Break
4:00 - 5:00: Joachim Stöhr: Industrial application of synchrotron radiation
5:00 - 6:30: Open discussion with all speakers, lecturers
7:30 - 9:00: Dinner
   
   








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